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Our genetic tests can identify patients who are most likely to respond to Immunotherapies and tap into the full potential of genome-based medicine.
Immunotherapy is an anti-cancer treatment that stimulates the reaction of our own immune system to cancer cells and is now a frontline treatment for many tumour types.
At London Medical Testing, we believe that Immunotherapy doesn’t work equally well for everyone: in some patients it appears to work incredibly well, completely destroying tumours even after they have begun to spread around the body, but for other patients the response can be less dramatic.
Therefore, in routine clinical practice it is necessary to establish if the patient will respond to immunotherapy treatments or not.
Immunofocus genetic tests can identify patients who are most likely to be able to tap into this type of genome-based cancer medicine.
Immunofocus TMB Test assesses the number of mutations (and the related number of neoantigens) in the cancer cell. The higher the tumour mutational burden, the higher the chance for the individual to respond to Immunotherapy.
Targeting the PD-1/PD-L1 connections with inhibitors has emerged as a powerful immunotherapy against these cancer types. Inhibiting the PD-1/PD-L1 pathway with therapeutic antibodies results in restoration of immune responses and activation of t-cells directed to kill the tumour cell.
Malfunctioning of the Mismatch Repair (MMR) pathway increases the mutational burden of specific cancers and is often involved in the cause of the malfunction, sometimes as an influential bystander and sometimes as the main driving force.
Immunofocus MMR Test analyses the Mismatch Repair genes (MLH1, MSH2, MSH6 and PMS2) to identify DNA repair defects linked to response to immunotherapy. The MMR test quickly identifies whether or not a new class of medicines will benefit you.
The MMR genetic test results provide the data needed to get access to the medicines through your oncologist or a clinical trial as quickly as possible. If the tests show that immunotherapy will benefit you, then the sooner you begin treatment the sooner you can start feeling better.
By determining the patients responsiveness to Immunotherapy solutions, Oncologica’s DNA tests can help patients find the therapy option that will work best for their tumour.
Immunofocus also helps patients avoid medication that will have little effect on their tumour and the side effects that could come from these types of therapy.
The cancer test allows your clinician to accurately identify the best treatment for your cancer.
Test may be requested by your hospital, doctor or oncologist. If your doctor is not aware of this test option, our patient consultants can guide you and suggest the best option to present to your doctor to obtain a test in your country.
As a clinician, you will have a powerful tool to optimise therapy choices and improve patient outcomes.
As a clinician you can register and request a test today. If you need more information or have any questions about the cancer test you can also request a consultation with our Support team.
London Medical Testing founded to assist the Government & other legal departments We are listed on the Gov.uk providers list for General.
To make a real difference to the health of United Kingdom by ensuring they have access to world-class medicines when they need them. To provide Central London.
We are committed to providing quick and easy access to DNA testing services, with results recognised by all public and private bodies.
All tests are administered by our team of doctors, nurses and healthcare professionals, CE Marked and approved by Public Health England, to ensure the highest level of safety and accuracy.
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